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Is it possible to overcome issues of external validity in preclinical animal research

Odorranalectin-conjugated nanoparticles: preparation, brain delivery and pharmacodynamic study on Parkinsons disease following intranasal administration

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[DOI] [PMC free article] [PubMed] [Google Scholar] 106.Prentice AM

A multi-strain probiotic formulation containing Streptococcus faecalis, Clostridium butyricum, Bacillus mesentericus , and Lactobacillus sporogenes , administered for 14 days reversed PTSD-like behaviors via MGBA restoration in mice (Khan et al., 2025)

Taking it daily, including rest days, may help maintain consistent levels and support overall metabolic processes